The key tables for any sort of database index tuning are :-
sys.dm_db_index_usage_stats
sys.dm_db_missing_index_details
sys.dm_db_missing_index_groups
sys.dm_db_missing_index_group_stats
Key point though - these statistics are cumulative since the last serve restart so don't try tuning on a cold server!
Resources
dm_db_index_usage_stats -
http://msdn.microsoft.com/en-us/library/ms188755.aspxdm_db_missing_index_details -
http://msdn.microsoft.com/en-us/library/ms345434.aspx dm_db_missing_index_groups
http://msdn.microsoft.com/en-us/library/ms345407.aspxdm_db_missing_index_group_stats
http://msdn.microsoft.com/en-us/library/ms345421.aspxNote that missing index details will be captured automatically unless SQL is started with the -x flag and that there are quite a few limitations to the missing indexes so if you've got over 500 missing index groups it's not really going to help you